Rational Design of Berberine-Based FtsZ Inhibitors with Broad-Spectrum Antibacterial Activity
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چکیده
منابع مشابه
Rational Design of Berberine-Based FtsZ Inhibitors with Broad-Spectrum Antibacterial Activity
Inhibition of the functional activity of Filamenting temperature-sensitive mutant Z (FtsZ) protein, an essential and highly conserved bacterial cytokinesis protein, is a promising approach for the development of a new class of antibacterial agents. Berberine, a benzylisoquinoline alkaloid widely used in traditional Chinese and native American medicines for its antimicrobial properties, has been...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0097514